We've been to both quite a bit. From our experience, XClub has generally been a younger 'party' crowd (25-40s mostly), OZone tends to be an older 'laid back' crowd (35-55+). Those were Saturday nights that we've experienced.
We generally agree that we prefer the atmosphere of OZone (more laid back), but like the eye-candy (and sometimes music) at XClub more. (We also definitely prefer the no-fuss locker-access at OZone too!)
If you can, try them both!